Sodium hyaluronat | Uro-Gial solution pH 6.5 – 7.5 bottle of 50 ml

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Release form



Bottle 50 ml.

Pharmacological action

Hyaluronic acid is a high molecular weight glycosaminoglycan that consists of repeating disaccharides N-acetylglucosamine and glucuronic acid. Hyaluronic acid is a part of all body tissues and is the most significant component of the intercellular matrix and, at the same time, makes up a significant proportion of glycosaminoglycans of urothelium of the bladder, urethra (urethra).

Medical device Uro-Gial is a viscoelastic protector of the intercellular substance of the urothelium of the bladder, urethra. When introduced into the cavity of the bladder, it creates a viscoelastic film on the surface of the mucous membrane that protects it from external influences during various manipulations (urethroscopy, cystoscopy, TUR of the prostate and bladder, radiation therapy of the pelvic organs, etc.).


Hypersensitivity to one of the components of the composition Uro-Gial,




Special instructions

The drug Uro-Gial is intended only for insertion into the cavity of the bladder using a urological catheter.

Vypot introduction, strictly observing the rules of asepsis.

Before use, check the integrity and tightness of the vial: do not use the product if the vial or its cap is damaged, and also check the integrity of the packaging of the syringe, needle and urological catheter. If they are damaged, the use of the drug is not permissible.

Do not use after the expiration date.

“URO-GIAL” is intended for instillation into the bladder, which must be performed by a doctor with special training in a specially equipped room, in compliance with all asepsis rules.

Composition of

1 ml of solution contains: sodium hyaluronate 0.8 mg, sodium dihydrogen phosphate monohydrate 0.4 mg, disodium phosphate anhydrous 2 mg, sodium chloride 8.5 mg В± 0.05, deionized water qs

Dosage and administration of

1. Obtain written informed consent from the patient for manipulation.

2. Explain to the patient the features of the procedure and intravesical instillation therapy (approximately as described below): a) if the source of pain is the bladder, then you can feel relief 5 to 15 minutes after the injection of

mixture b) in the initial phase of treatment You may need intravesical instillations more often than 1 time per week.

c) try to keep the injected mixture in your bladder for at least 30 minutes, but not more than 2 hours.

d) sometimes (rarely) side effects occur, which you should immediately notify your doctor.

d) extremely rare, there is a recoil effect, when after 5 – 6 hours after administration of the drug, the pain returns with greater intensity.

e) instillation therapy may require more procedures than planned.

3. Prepare the patient for catheterization on the urogynecological chair.

4. Wash your hands. Wear non-sterile gloves.

5. Treat the external opening of the urethra with an antiseptic.

6. Insert a lubricant anesthetic into the urethra, leaving a small amount of gel to lubricate the catheter.

7. Take off your gloves.

8. Wash your hands.

9.Fill the preparation (s) in a 60 ml syringe. (If a combination of drugs is used, then pre-mix them in a bottle with URO-GIAL using a 10 ml syringe).

10.Open the catheter package.

11. Put on sterile gloves.

12. While maintaining sterility, apply a small amount of anesthetic lubricant to the tip of the catheter and gently insert the catheter into the urethra and further into the bladder.

13. Empty the bladder, then attach the syringe to the catheter and slowly inject the solution into the bladder.

14. Remove the catheter from the urethra.

15. Throw away used accessories in special containers.

16. Remove the gloves.

17. Wash your hands.

18. Record on an outpatient card and assign patient.

“URO-GIAL” is administered intravesically, 1 time per week. The course is from 4 to 12 instillations.

The vial should be removed from the refrigerator at least 20 minutes before use. Before use, the temperature of the bottle should be at least 20C.

Before administration of the URO-GIAL preparation, the bladder should be emptied.

The URO-GIAL preparation is injected into the bladder cavity using a urological catheter for a period of at least 30 minutes.

Side effects

No side effects have been identified. Individual intolerance may be observed.

Drug interaction

Incompatibility between sodium hyaluronate and quaternary ammonium chloride salts such as ammonium chloride, such as. Uro-Gial should not be allowed to come into contact with such drugs or with medical and surgical instruments treated with such drugs.

Storage conditions

Store at a temperature of +2 ° C to +15 ° C.

Deystvuyuschee substances

Sodium hyaluronat

dosage form

infusion solution

Additional information


2 reviews for Sodium hyaluronat | Uro-Gial solution pH 6.5 – 7.5 bottle of 50 ml

  1. Monica


  2. Alisha

    Thank you

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