Ointment for external use 5%.
Non-steroidal anti-inflammatory drug, has anti-inflammatory and analgesic effects. Indirectly inhibits the activity of cyclooxygenases (COX-1 and COX-2) and inhibits the synthesis of prostaglandins.
Phenylbutazone inhibits the synthesis of ATP-dependent mucopolysaccharides.
Butadion is used to eliminate pain and reduce swelling associated with the inflammatory process. When applied topically, it causes the weakening or disappearance of joint pain at rest and during movement.
Reduces morning stiffness and swelling of joints, helps increase range of motion.
Post-traumatic inflammation of the soft tissues and joints, for example, as a result of sprains, strains and bruises.
Rheumatic diseases of soft tissues (tendovaginitis, bursitis, damage to periarticular tissues), muscle pains of rheumatic and non-rheumatic origin.
Pain and swelling associated with diseases of the muscles and joints.
Data on an attack of bronchial obstruction, allergic rhinitis, urticaria after taking acetylsalicylic acid or other NSAIDs in history.
I and III trimesters of pregnancy.
Violation of the integrity of the skin at the site of the alleged application.
Children under 14 years old.
Concomitant use with other drugs containing phenylbutazone.
Hypersensitivity to phenylbutazone or other components of the drug, to acetylsalicylic acid and other NSAIDs.
If skin redness occurs, therapy should be discontinued.
Ointment should only be applied to intact skin, avoiding contact with open wounds. After application, an occlusive dressing should not be applied. Do not allow the drug to enter the eyes and mucous membranes.
The drug should not be used to treat deep vein thrombophlebitis. To prevent photosensitivity, protect your skin from direct sunlight. When used together with other dosage forms of Butadion, the maximum daily dose of this drug should be considered.
Influence on the ability to drive vehicles and control mechanisms
Data on the influence of Butadion on the ability to drive a car and engage in other activities that require concentration and speed of psychomotor reactions are not provided.
1 g of ointment contains:
phenylbutazone 50 mg.
sodium carboxymethyl cellulose,
silicon dioxide colloidal,
Dosage and Administration
Adults and children over the age of 14 years: the drug is applied in a thin layer, a strip of 2-3 cm above the focus of inflammation without rubbing 2-3 times / day. The course of treatment is 7-10 days. After 10 days of use, consult a doctor.
Elderly patients: no special regimen is needed.
Local reactions: eczema, photosensitivity, contact dermatitis (itching, redness, puffiness of the treated area of ââthe skin of papules, vesicles, peeling.
Allergic reactions: urticaria, angioedema, bronchospasm, generalized skin rash.
No clinically significant interaction of Butadion with other drugs has been established.
The use of Butadione with other NSAIDs should be avoided.
Butadione may potentiate photosensitizing drugs.
Extremely low absorption of the active components of the drug when used externally makes overdosage virtually impossible.
Symptoms: Systemic adverse reactions characteristic of NSAIDs may occur if swallowed large amounts of ointment (more than 20 g) are accidentally swallowed.
Treatment: gastric lavage, activated charcoal required.
Store at 8 to 15 ° C out of the reach of children.
Conditions of drugstore
For adults, Pregnant only II trimester as prescribed by a doctor, Children older than 15 years