Spray for external use.
Bottle 60 ml.
Generolone – a treatment for alopecia. When applied topically, minoxidil stimulates hair growth in individuals with androgenetic alopecia (hair thinning, alopecia). It improves microcirculation, stimulates the transition of hair cells into an active growing phase, and alters the effect of androgens on hair sacs.
Reduces the formation of 5-alpha-dehydrosterone (possibly indirectly), which plays a significant role in the formation of baldness. It has the best effect with a short prescription of the disease (no more than 10 years), young patients, bald spot in the crown no more than 10 cm, the presence in the center of the bald head of more than 100 fluff and terminal hair.
The manifestation of signs of hair growth is noted after 4 or more months of use of the drug. The onset and severity of the effect may vary in different patients. A 5% solution of the drug stimulates hair growth more than a 2% solution, which was noted by an increase in the growth of gun hair. After stopping the use of the drug Generolop, the growth of new hair is suspended, and within 3-4 months it is possible to restore the original appearance.
The exact mechanism of action of the drug Generalon in the treatment of androgenetic alopecia is unknown. Minoxidil is ineffective in case of baldness caused by taking the drug, improper nutrition (iron (Fe) deficiency, vitamin A), as a result of styling hair in tight hairstyles.
Treatment of androgenetic alopecia (hair restoration) and stabilization of hair loss in men and women.
Hypersensitivity to minoxidil or other components of the drug under the age of 18 years, violation of the integrity of the skin, dermatosis of the scalp.
Use during pregnancy and lactation
The drug should not be used during pregnancy and lactation.
Do not apply to other parts of the body.
The drug Generolon is applied only to dry skin of the hairy hPart of the head after bathing or should wait about 4 hours after applying the drug before bathing. Do not let your head get wet earlier than 4 hours after applying the drug.
It is recommended to wash hair when using the drug Generolon in the usual way. During the period of use, the drug Generolon can be used with hairspray and other hair care products. Before applying hair care products, you must first apply the drug Generolon and wait until the treated area of Ð²Ðâ¹Ð²Ðâ¹the skin is completely dry. There is no evidence that dyeing hair, perming or using hair softeners can reduce the effectiveness of the drug. However, to prevent possible irritation of the scalp, make sure that the drug was completely washed off from the hair and scalp before using these chemicals.
Before starting treatment with the drug Generolon, patients should undergo a general examination, including the collection and study of a medical history. The doctor must make sure that the scalp is healthy.
If systemic side effects or severe skin reactions occur, patients should discontinue the drug and consult a doctor.
Generolone contains ethyl alcohol, which can cause inflammation and irritation of the eyes. In case of contact with sensitive surfaces (eyes, irritated skin, mucous membranes), rinse the area with plenty of cold water.
Avoid inhalation of the drug when sprayed.
After using the drug, wash your hands thoroughly.
1 ml of solution contains:
minoxidil – 20.00 mg
excipients: srd %) – 571.00 / 243.00 mg,
propylene glycol – 104.00 / 520.00 mg,
water – up to 1 ml.
Dosage and Administration
Regardless of the size of the treated area, it is necessary to apply 1 ml of the solution with a dispenser (7 presses) 2 times a day to the affected areas of the scalp, starting from the center of the problem area. Wash hands after use. The total daily dose should not exceed 2 mg (the dose does not depend on the size of the affected area). For patients who, when using a 2% solution, satisfactory hair growth is not observed, and for patients who want faster hair growth, a 5% solution can be used.
For men, the drug Generolon is most effective for hair loss on the crown, for women – for hair loss in the middle parting.
The drug Generolon is applied only to dry skin of the scalp. The solution does not require rinsing.
The appearance of the first signs of stimulation of hair growth is possible after using the drug 2 times a day for 4 months or more. The onset and severity of hair growth, as well as the quality of hair, may vary in different patients.
According to single reports, within 3-4 months after discontinuation of treatment, restoration of the initial appearance can be expected. The average duration of treatment is about 1 year.
Local side effects:
The most common side effect is dermatitis of the scalp. Less common are more pronounced cases of dermatitis, manifested in the form of redness, peeling and inflammation. In rare cases, itching of the head, allergic contact dermatitis, folliculitis, hypertrichosis (unwanted body hair growth, including facial hair growth in women), seborrhea are noted.
The use of minoxidil can cause increased hair loss during the transition from the resting phase to the hair growth phase, while old hair falls out and new ones grow in their place. This temporary phenomenon is usually observed 2-6 weeks after the start of treatment and gradually stops within the next 2 weeks (the appearance of the first signs of the action of minoxidil).
Systemic side effects (if the drug is accidentally swallowed):
Dermatological diseases: nonspecific allergic reactions (skin rash, urticaria), swelling of the face.
Respiratory system: shortness of breath, allergic rhinitis.
Nervous system: headache, dizziness, vertigo, neuritis.
Cardiovascular system: chest pain, fluctuations in blood pressure, heart palpitations, changes in heart rate, edema.
There is a theoretical possibility (no clinical evidence) of enhancing orthostatic hypotension in patients. receiving concomitant treatment with peripheral vasodilators.
It is impossible to exclude a very slight increase in the content of minoxidil in the blood of patients, suffering from arterial hypertension and taking minoxidil orally in case of simultaneous use of the drug Generolon, although relevant clinical studies have not been conducted.
It has been found that minoxidil for external use may interact with certain drugs for external use. The simultaneous use of a solution of minoxidil for external use and a cream containing betamethasone (0.05%) leads to a decrease in the systemic absorption of minoxidil.
The simultaneous use of a cream containing tretinoin (0.05%). leads to increased absorption of minoxidil. The simultaneous application of minoxidil and topical preparations, such as tretinoin and dithranol, to the skin, which cause a change in the protective functions of the skin, can lead to an increase in the absorption of minoxidil.
Accidental ingestion Generolone can cause systemic side effects due to vasodilating properties of minoxidil (5 ml of 2% solution contains 100 mg of minoxidil – maximum recommended dose for adults 5 ml in adults) The solution contains 250 mg of minoxidil, ie a dose 2.5 times the maximum recommended daily dose for adults when taken orally in the treatment of hypertension).
Signs of overdose: fluid retention, decreased blood pressure, tachycardia.
Treatment: To eliminate fluid retention, diuretics can be prescribed if necessary for the treatment of tachycardia – beta-adrenal locators. 0.9% sodium chloride solution should be administered intravenously for the treatment of hypotension.
Do not use simiatomimetics, for example. norepinephrine and epinephrine having excessive cardio-stimulating activity.
At a temperature not exceeding 25 ° C. Keep out of reach of children!
Terms and conditions
spray for topical use
Possible product names
GENEROLON 2% 60ML SPRAY
GENEROLON R-R OUTDOOR. 2% 60ML
GENEROLON SPRAY 2% 60ML. FL
GENEROLON SPRAY D / NAR. NOTE 2% FL. 60ML No. 1
Generolon spray d / nar.pr. 2% 60ml
Belupo, medicines and cosmetics d.d, Croatia