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Levocetirizine | Suprastinex drops for oral administration 5 mg /ml 20 ml

(4 customer reviews)

$27.00 $19.00

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Description

Release form

Drops for oral administration.

Packaging

Bottle 20 ml.

Pharmacological action

Suprastinex – a blocker of histamine H1 receptors. Levocetirizine is the enantiomer of cetirizine, a competitive histamine antagonist. It blocks H1-histamine receptors, the affinity for which is 2 times higher than that of cetirizine. It has an effect on the histamine-dependent stage of allergic reactions, reduces eosinophil migration, reduces vascular permeability, and limits the release of inflammatory mediators. It prevents the development and facilitates the course of allergic reactions, has an antiexudative, antipruritic effect. Virtually no anticholinergic and antiserotonergic effects. In therapeutic doses, it has practically no sedative effect.

Indications

Symptomatic treatment:

– Year-round and seasonal allergic rhinitis and conjunctivitis (pruritus, sneezing, rhinorrhea, lacrimation, conjunctival hyperemia).

– Hay fever (hay fever).

– Urticaria, including chronic idiopathic urticaria.

– Quincke’s edema.

– Allergic dermatoses, accompanied by itching and rashes.

Contraindications

– Severe renal failure (CC less than 10 ml / min).

– Children under 6 years of age (for this dosage form).

– Pregnancy.

– Lactation.

– Lactose intolerance, hereditary lapp lactase deficiency lapp (lactase deficiency in some peoples of the North) or glucose-galactose malabsorption syndrome (due to the content of lactose in the tablets).

– Hypersensitivity to the active (including piperazine derivatives) or any auxiliary component of the drug.

Caution should be used in: – Chronic renal failure.

– Elderly patients (possibly reduced glomerular filtration).

Pregnancy and lactation

Animal studies have not shown a direct or indirect harmful effect on pregnancy, fetal or fetal development, childbirth or postnatal development. There have been no controlled clinical trials on the safety of the drug in pregnant women, so the drug should not be prescribed during pregnancy.

Levocetirizine is excreted in breast milk, so if it is necessary to use it during lactation, breastfeeding should be discontinued while taking the drug.

Special instructions

Influence on the ability to drive vehicles and operate machinery: during the treatment period it is recommended to refrain from engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

Composition

1 ml drops contains: levocetirizine dihydrochloride 5 mg.

Excipients: glycerol 85%, propylene glycol, sodium saccharinate, sodium acetate trihydrate, methyl parahydroxybenzoate, propyl parahydroxybenzoate, glacial acetic acid, purified water.

Dosage and Administration

The drug should be taken orally with food or on an empty stomach. Drops should be taken orally immediately after dilution. The daily dose is recommended to be taken in 1 dose. The recommended dose for adults and children over 6 years old, elderly patients (subject to normal kidney function) is 5 mg – 1 ml drops or 20 drops from a dropper per day. For children aged 2 to 6 years, the drug is prescribed in the form of drops. The daily recommended dose is 2.5 mg in 2 divided doses in 1.25 mg equal doses (2 times 0.25 ml drops = 2 x 5 drops from a dropper). The duration of administration depends on the disease. The course of treatment of hay fever on average is 1-6 weeks. In chronic diseases (year-round rhinitis, chronic idiopathic urticaria), the course of treatment can be increased. There is clinical experience with the use of the drug up to 18 months.

Side effects of

Metabolism: very rarely – weight gain.

From the side of the central nervous system: often – drowsiness, headache, increased fatigue infrequently – asthenia rarely – migraine, dizziness.

From the respiratory system: very rarely – dyspnea.

From the digestive system: often – dry mouth is rare – abdominal pain is very rare – nausea, dyspepsia, changes in functional liver tests.

Allergic reactions: very rarely – anaphylaxis, angioedema, pruritus, rash, urticaria.

Drug Interactions

Studies of the interaction of levocetirizine have shown no clinically significant interaction with pseudoephedrine, cimetidine, ketoconazole, erythromycin, azithromycin, glipizide and diazepam. Joint use with macrolides or ketoconazole did not cause significant changes on the ECG.

Theophylline (400 mg /) reduces the total clearance of levocetirizine by 16%. The pharmacokinetics of theophylline does not change.

Levocetirizine does not enhance the effects of ethanol, however, in sensitive patients, concomitant use of levocetirizine with ethanol or other central nervous system depressants may affect the central nervous system.

overdose

Symptoms: overdoses in adults are drowsy, in children – excitement, anxiety, which are replaced by drowsiness.

Treatment: There is no specific antidote. Symptomatic and supportive therapy is recommended, gastric lavage. Hemodialysis is ineffective.

Storage Conditions

Do not store above 25 ° C. Do not freeze.

active substance

Levocetirizine

lekarstvennaja form

Drops for pryema inside

Prescribing

For Adults, Children over 2 years of age

Additional information

Brand

4 reviews for Levocetirizine | Suprastinex drops for oral administration 5 mg /ml 20 ml

  1. Joshua

    Fast shipping.

  2. Tony

    Very fast and good store. Item as photo.

  3. Amy

    Excellent seller.

  4. Mary

    *********************** many thanks 10/10 ***********************************

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