Syrup for children
Bottle 125 ml.
Pharmacological action of
Carbocysteine, being a mucolytic, acts on the gel phase of the endobronchial secretion, breaking the disulfide bridges of glycoproteins and, thus, reducing viscosity and increasing the elasticity of the secretion.
Carbocysteine ââactivates sialic transferase, an enzyme of goblet cells of the bronchial mucosa, normalizes the quantitative ratio of acid and neutral sialomucins, promotes the regeneration of the mucous membrane, normalizes its structure, activates the activity of ciliary epithelium, restores the secretion of immunologically active IgA (specific protection), improves mucocytes.
Carbocysteine ââis rapidly absorbed after oral administration, reaching a maximum level in serum after 2 hours. Bioavailability is low (less than 10% of the dose taken) as a result of a possible rapid passage through the liver. The elimination half-life is about 2 hours. It is excreted mainly by the kidneys along with metabolites.
Acute and chronic bronchopulmonary diseases accompanied by the formation of a viscous, difficult to separate sputum (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectatic disease) and mucus (inflammatory diseases of the middle ear, nose and sinuses – rhinitis, otitis media, sinusitis) preparing the patient for bronchoscopy or bronchography.
Peptic ulcer of the stomach and duodenum in the acute stage
chronic glomeruritis (in the acute phase), cystitis
children under 2 years of age
hypersensitivity to another component of the drug.
With caution, a history of gastric and duodenal ulcer, a history of lactation.
The alcohol content in Libexin MucoÐÂ® (for adults) is 1.64 vol.%, i.e. 0.2 g of alcohol per measuring cup. May be dangerous for people with liver disease, alcoholism, epilepsy, injuries or diseases of the brain, pregnant women.
When prescribing Libexin MukoÐÂ® to patients with diabetes mellitus or to patients on a low-carb diet, the sucrose content should be taken into account – 6 g per measuring cup of adult syrup or 3.5 g per measuring spoon of syrup for children.
If patients follow a salt-free or low-salt diet, the sodium content (97 mg) per cup should be taken into account.
Influence on the ability to drive a car or perform work that requires an increased speed of physical and mental reactions. Violation of the speed of psychomotor reactions associated with the presence of alcohol in the drug can be dangerous when driving a car or working with machinery.
100 ml of syrup contains:
Active ingredient: carbocysteine ??2 g
sucrose – 70 g
methyl parahydroxybenzoate – 0.15 g
vanillin – 0, 05 g
crimson dye Ponceau 4R (cochineal red A – E124) – 0.005 g
raspberry flavor – 1 ml
cherry flavor – 0.5 ml
sodium hydroxide – qs to pH 6.16.3
purified water – until 100 ml
Dosage and Administration
One measuring cup of syrup (15 ml) contains 750 mg of carbocysteine, 1 measuring spoon (5 ml) – 100 mg of carbocysteine.
Adults – one measuring cup (15 ml) 3 times a day, preferably separately from meals for children 2â5 years old – 1 scoop 2 times a day (200 mg / day), over 5 years old – 1 scoop 3 times a day (300 mg / day).
The duration of treatment without consulting a doctor should not exceed 8 days.
From the digestive tract: sometimes – nausea, vomiting, diarrhea, epigastric pain, gastrointestinal bleeding.
On the part of the immune system: allergic skin rash and anaphylactic reactions, including urticaria, angioedema, exanthema, persistent drug erythema.
From the skin and subcutaneous tissues: isolated cases of bullous dermatitis, including Stevens-Johnson syndrome and erythema multiforme (exudative).
Allergic reactions: itching, urticaria, exanthema, angioedema.
Other: dizziness, weakness, malaise.
Carbocysteine ââincreases the effectiveness of corticosteroids and antibacterial therapy of inflammatory diseases of the upper and lower respiratory tract, potentiates the bronchodilator effect of theophylline. The activity of carbocysteine ââis weakened by antitussive and atropine-like drugs.
Due to its alcohol content, Libexin MukoÂ® (for adults) is prescribed with caution with the following drugs: drugs that cause adverse reactions (fever, redness, vomiting, tachycardia) when taken with alcoholic beverages – disulfiram, cefamandol, cefoperazone, latamoxef (cephalosporin antibiotics), chloramphenicol (phenolic antibiotic), chlorpropamide, glibenclamide, glipizide, tolbutamide (sulfamide antidiabetic drugs), griseofulvin (antifungal drug), nitro-5-imidazoles (metronidazole, ornidazole, secnidazole, tinidazole), ketoconazole, procarbazine (cytostatic) drugs that depress the central nervous system.
Symptoms: gastralgia, nausea, diarrhea.
At a temperature not exceeding 25 ° C.
Conditions of sale from drugstore
solution for oral administration
Possible product names
Libexin Muco syrup for children 20 mg / ml 125 ml
A. Nattermann & Sie GmbH, Germany