Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It has anti-inflammatory, analgesic and antipyretic effects. It inhibits the COX enzyme in the cascade of arachidonic acid metabolism and disrupts the biosynthesis of prostaglandins.
When used externally, it has anti-inflammatory and analgesic effects. Reduces and relieves pain at the site of ointment application (including joint pain at rest and during movement), reduces morning stiffness and swelling of joints. Helps increase range of motion.
pathological changes in the blood picture of unclear genesis
gastric ulcer and duodenal ulcer lactation period (breast-feeding should be abandoned)
children and adolescents under 12 years of age (i / m administration, supp.)
children d about 6 years (tablets, ointment)
hypersensitivity to acetylsalicylic acid or other NSAIDs (including aspirin triad)
hypersensitivity to diclofenac and other components of the drug
inflammation of the rectum – proctitis (suppositories)
Active ingredient: diclofenac sodium 50 mg
Dosage and administration
At a dose of 2-4 g, a thin layer is applied to the skin over the site of inflammation and gently rubbed, the frequency of use is 2-3 times a day.
The maximum daily dose of ointment should not exceed 8 g.
The course of treatment is no more than 14 days. The need for a longer use of the drug is determined by the doctor.
Skin rashes, burning, redness are possible at the application site. With prolonged external use of the drug, it is possible to develop systemic side effects from the digestive system, central nervous system, respiratory system, as well as allergic reactions.
With simultaneous use of the drug Diclofenac with digoxin, phenytoin or lithium drugs, it is possible to increase the plasma concentrations of these drugs with diuretics and antihypertensive drugs – it is possible to decrease the effects of these drugs with diuretics and diuretics – possible development of hyperkalemia with acetisalicylic acid – a decrease in the concentration of diclofenac in blood plasma and an increased risk of side effects.
Diclofenac may enhance the toxic effects of cyclosporine on the kidneys.
Diclofenk may cause hypo- or hyperglycemia, therefore, with simultaneous use with hypoglycemic agents, control of the concentration of glucose in the blood is required.
When methotrexate is used within 24 hours before or after taking Diclofenac, an increase in the concentration of methotrexate and an increase in its toxic effect are possible.
With simultaneous use with anticoagulants, regular monitoring of blood coagulation is necessary.
in a dry, dark place at a temperature of no more than 9 ° C at 950 ° C 8 to 15 ° C. Freezing is not allowed.
Without a prescription
Dosage Form Gel for external use
Synthesis AKOMP, Russia