Atypamezol | Antimedin injection solution Api-San bottle (BET) 10 ml

(6 customer reviews)

$48.00 $37.00

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Pharmacological action

Antimedin belongs to the group of alpha2 antagonists. Atipamezole hydrochloride – the active ingredient of Antimedin – selectively blocks alpha2 receptors (alpha2 antagonist), which causes the release of norepinephrine in the central and peripheral nervous system. This leads to stimulation of the sympathetic nervous system, as a result of which the sedative effect of medetomidine hydrochloride (Meditin), which activates alpha2 receptors, is eliminated. Antimedin is rapidly absorbed after intramuscular injection and after 10-15 minutes reaches its maximum concentration in the blood. Atipamezole hydrochloride is metabolized mainly in the liver, a smaller part – in the kidneys. Excreted mainly in the urine in the form of metabolites. The elimination half-life is 1 hour.


Antimedin is used to eliminate the sedative and analgesic effects of medetomidine in dogs and cats, as well as to eliminate the side effects of medetomidine on the cardiovascular and respiratory systems. Antimedin is used 15-60 minutes after alpha2-agonists. Usually, the sedative effect of medetomidine or dexamedetomidine is removed within 5-10 minutes.


Contraindication to use is heart failure, impaired liver or kidney function. The drug is not used for pregnant and lactating females. Antimedin is not used to eliminate the effects of other sedatives.

Composition of

in 1 ml as active ingredient 5 mg of atipamisole hydrochloride.

Dosage and administration of

Antimedin is administered to animals intramuscularly once. In the case of an ongoing depressed state in the animal, it is possible to reintroduce Antimedin in 10-15 minutes. Dosages: for dogs, the dose of Antimedin in ml is equal to the dose of medetomidine administered. for cats, the dose of Antimedin in ml is equal to half the administered dose of medetomidine.

Active ingredient


Additional information


6 reviews for Atypamezol | Antimedin injection solution Api-San bottle (BET) 10 ml

  1. Marcy

    Good transaction

  2. Jeremy

    good product

  3. Rosie


  4. Roberto

    Item as described, thank you

  5. Scott

    Perfect! Exactly what I wanted and needed!

  6. Denise

    as stated

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